| J. Hurts | QB |  Valenzuela,  Bronchtein | 2020–2025 | 53 | 1054.3 | 19.9 |
| L. McCoy | RB |  Wessel,  Ballard,  Becker-Parton,  Wright, Valenzuela | 2010–2014 | 77 | 1008.7 | 13.1 |
| C. Wentz | QB | Becker-Parton,  Banys,  Waxman, Wright,  Norberg | 2016–2020 | 71 | 978.0 | 13.8 |
| Z. Ertz | TE | Ballard, Wright, Banys,  Freundlich, Becker-Parton, Bronchtein, Norberg, Waxman | 2013–2020 | 91 | 764.1 | 8.4 |
| A. Brown | WR | Becker-Parton,  Sohl,  Foote | 2022–2025 | 50 | 648.6 | 13.0 |
| M. Vick | QB | Freundlich,  Demarkis, Wright,  Baumann, Ballard | 2010–2013 | 49 | 647.7 | 13.2 |
| Jalen Hurts | QB | Baumann, Bronchtein | 2021–2024 | 34 | 613.3 | 18.0 |
| J. Maclin | WR | Baumann, Ballard, Foote, Freundlich | 2010–2014 | 62 | 548.4 | 8.8 |
| D. Smith | WR |  Kassel, Waxman, Ballard | 2022–2025 | 51 | 540.6 | 10.6 |
| D. Jackson | WR | Bronchtein,  Wood, Freundlich, Ballard, Valenzuela, Waxman | 2010–2020 | 72 | 539.5 | 7.5 |
| D. Goedert | TE | Becker-Parton, Waxman, Sohl,  Faust, Ballard | 2018–2025 | 70 | 483.7 | 6.9 |
| S. Barkley | RB | Baumann, Wright, Valenzuela | 2023–2025 | 33 | 389.1 | 11.8 |
| J. Elliott | K | Valenzuela,  Rath, Baumann, Becker-Parton, Wright, Waxman, Faust | 2017–2025 | 53 | 379.0 | 7.2 |
| A. Jeffery | WR | Foote, Banys, Waxman | 2017–2020 | 50 | 372.3 | 7.4 |
| D. Sproles | RB | Wood, Baumann, Banys, Norberg, Becker-Parton | 2014–2018 | 64 | 343.0 | 5.4 |
| Saquon Barkley | RB | Ballard | 2024 | 17 | 338.8 | 19.9 |
| A.J. Brown | WR | Baumann,  P. Waxman | 2021–2024 | 34 | 318.0 | 9.4 |
| M. Sanders | RB | Valenzuela | 2019–2020 | 31 | 311.3 | 10.0 |
| N. Agholor | WR | Banys, Becker-Parton, Rath, Sohl, Bronchtein | 2015–2019 | 58 | 311.2 | 5.4 |
| DeVonta Smith | WR | Freundlich, Foote | 2021–2024 | 33 | 305.3 | 9.3 |
| J. Matthews | WR | Becker-Parton, Bronchtein, Baumann, Wright | 2014–2016 | 43 | 303.0 | 7.0 |
| N. Foles | QB | Wood | 2013–2014 | 19 | 301.5 | 15.9 |
| R. Mathews | RB | Foote, Ballard | 2015–2016 | 31 | 230.1 | 7.4 |
| Dallas Goedert | TE | Freundlich, Faust, P. Waxman | 2021–2024 | 29 | 194.2 | 6.7 |
| D. Swift | RB | Valenzuela | 2022 | 17 | 155.0 | 9.1 |
| J. Ajayi | RB | Norberg, Baumann | 2017–2018 | 20 | 154.1 | 7.7 |
| G. Tate | WR | Ballard | 2018 | 15 | 139.4 | 9.3 |
| B. Celek | TE | Banys, Wood, Freundlich, Wright, Becker-Parton | 2010–2013 | 24 | 131.4 | 5.5 |
| D. Murray | RB | Waxman | 2015 | 15 | 129.2 | 8.6 |
| C. Parkey | K | Banys, Ballard | 2014–2015 | 15 | 123.0 | 8.2 |
| Jake Elliott | K | Valenzuela, Faust, Freundlich, Bronchtein | 2021–2024 | 15 | 116.0 | 7.7 |
| M. Mariota | QB | Becker-Parton, Wright, Baumann | 2022 | 9 | 111.7 | 12.4 |
| D. Akers | K | Foote, Baumann | 2010 | 13 | 110.0 | 8.5 |
| S. Bradford | QB | Wright | 2015 | 11 | 107.0 | 9.7 |
| J. Howard | RB | Banys | 2019 | 15 | 106.4 | 7.1 |
| Miles Sanders | RB | P. Waxman | 2021 | 17 | 104.2 | 6.1 |
| M. Sanchez | QB | Baumann | 2014 | 7 | 99.0 | 14.1 |
| C. Sturgis | K | Foote, Bronchtein | 2016–2017 | 11 | 90.0 | 8.2 |
| L. Blount | RB | Wright, Ballard | 2017 | 15 | 85.6 | 5.7 |
| R. Cooper | WR | Wood, Banys, Waxman | 2011–2014 | 12 | 76.2 | 6.4 |
| B. Brown | RB | Becker-Parton, Wright, Baumann | 2012–2013 | 12 | 75.7 | 6.3 |
| K. Gainwell | RB | P. Waxman, Banys, Valenzuela, Faust | 2022–2023 | 17 | 74.5 | 4.4 |
| W. Smallwood | RB | Banys, Becker-Parton, Wright | 2016–2018 | 19 | 72.9 | 3.8 |
| A. Henery | K | Baumann, Becker-Parton, Wright | 2011–2013 | 9 | 71.0 | 7.9 |
| R. Penny | RB | Ballard | 2022 | 9 | 50.2 | 5.6 |
| T. Fulgham | WR | Valenzuela | 2020 | 8 | 48.3 | 6.0 |
| Kenneth Gainwell | RB | Becker-Parton, Waxman, P. Waxman | 2021 | 7 | 46.6 | 6.7 |
| J. Adams | RB | Baumann, Wright | 2018 | 5 | 33.8 | 6.8 |
| J. Harrison | RB | Norberg | 2010 | 13 | 32.9 | 2.5 |
| B. Scott | RB | Valenzuela, Wright | 2020 | 4 | 32.0 | 8.0 |
| C. Clement | RB | Becker-Parton, Freundlich | 2018 | 6 | 28.9 | 4.8 |
| Jordan Howard | RB | Becker-Parton, Wright | 2021 | 3 | 24.0 | 8.0 |
| Boston Scott | RB | Freundlich, Becker-Parton | 2021 | 4 | 22.0 | 5.5 |
| V. Young | QB | Freundlich | 2011 | 1 | 12.8 | 12.8 |
| Zach Pascal | WR | Faust | 2021 | 2 | 12.7 | 6.4 |
| T. Bigsby | RB | Waxman, Valenzuela | 2025 | 10 | 12.2 | 1.2 |
| J. Reagor | WR | Norberg | 2020 | 5 | 12.1 | 2.4 |
| D. Green-Beckham | WR | Norberg | 2016 | 5 | 10.8 | 2.2 |
| J. Avant | WR | Wood, Bronchtein | 2011–2013 | 6 | 9.6 | 1.6 |
| D. Parker | WR | P. Waxman | 2023 | 2 | 7.2 | 3.6 |
| W. Shipley | RB | Faust | 2025 | 2 | 2.6 | 1.3 |
| Gardner Minshew | QB | Baumann | 2021 | 3 | 0.0 | 0.0 |
| Jahan Dotson | WR | Freundlich | 2024 | 1 | 0.0 | 0.0 |